The White House released a brief statement on 8 April 2021, commenting that National Security Advisor Jake Sullivan spoke by phone on 7 April with Ethiopian Deputy Prime Minister Demeke Mekonnen. Sullivan expressed "the Biden Administration's grave concern about the continued humanitarian and human rights crisis in the Tigray region." They discussed steps to address the crisis, including expanded humanitarian access, cessation of hostilities, departure of foreign troops, and independent investigations of atrocities. Sullivan said the United States is ready to help Ethiopia address its border dispute with Sudan and the issue of the Grand Ethiopian Renaissance Dam.
The Hill published on 8 April 2021 an article titled "US Expresses 'Grave Concern' over Harrowing Reports of Atrocities in Ethiopia" by Laura Kelly. This article expands on the White House statement.